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Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser2) Rabbit pAb

Cat No.: DPA05360
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Product Name: Phospho-RNA polymerase II CTD repeat YSPTSPS (Ser2) Rabbit pAb
Cat No.: DPA05360
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:50
FC: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser2 of human RNA polymerase II CTD
Calculated Molecular Weight: 192 kDa
Observed Molecular Weight: 250 kDa
GenBank Accession Number: P24928
Gene ID (NCBI): 5430
Synonyms: RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; NEDHIB; RpIILS; hsRPB1; hRPB220
Background: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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