蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Bad Rabbit pAb
Cat#:DPA01351应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-Bad (Ser112) Rabbit pAb |
| Cat No.: | DPA05386 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:2000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser112 of human Bad |
| Calculated Molecular Weight: | 18 kDa |
| Observed Molecular Weight: | 23 kDa |
| GenBank Accession Number: | Q92934 |
| Gene ID (NCBI): | 572 |
| Synonyms: | BBC2; BCL2L8 |
| Background: | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019] |
| Category: | Primary Ab |
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