蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human CRK Protein
Cat#:TP01713应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-Crk p38 (Tyr221) Rabbit pAb |
| Cat No.: | DPA05406 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr221 of human Crk p38 |
| Calculated Molecular Weight: | 34 kDa |
| Observed Molecular Weight: | 38 kDa |
| GenBank Accession Number: | P46108 |
| Gene ID (NCBI): | 1398 |
| Synonyms: | p38; CRKII |
| Background: | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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