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查看说明书EGFR Rabbit pAb
Cat#:DPA02484应用：WB,ICC/IF,FC
| Product Name: | Phospho-EGFR (Tyr1086) Rabbit pAb |
| Cat No.: | DPA05419 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:10001:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr1086 of human EGFR |
| Calculated Molecular Weight: | 134 kDa |
| Observed Molecular Weight: | 175 kDa |
| GenBank Accession Number: | P00533 |
| Gene ID (NCBI): | 1956 |
| Synonyms: | ERBB; HER1; mENA; ERBB1; PIG61; NISBD2 |
| Background: | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020] |
| Category: | Primary Ab |
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