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查看说明书Recombinant Human Insulin Receptor / INSR / CD220 Protein (short isoform, His tag)
Cat#:TP07950应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-Insulin Receptor (Tyr1185) Rabbit pAb |
| Cat No.: | DPA05432 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr1185 of human Insulin Receptor |
| Calculated Molecular Weight: | 156 kDa |
| Observed Molecular Weight: | 95 kDa |
| GenBank Accession Number: | P06213 |
| Gene ID (NCBI): | 3643 |
| Synonyms: | HHF5; CD220 |
| Background: | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Category: | Primary Ab |
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