Histone H2A.X Rabbit pAb
Cat#:DPA01143应用:WB,IHC,ICC/IF,FC,IP
Product Name: | Phospho-Histone H2A.X (Ser139) Rabbit pAb |
Cat No.: | DPA05435 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,IP |
Recommended Dilution: | WB: 1:2000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X |
Calculated Molecular Weight: | 15 kDa |
Observed Molecular Weight: | 15 kDa |
GenBank Accession Number: | P16104 |
Gene ID (NCBI): | 3014 |
Synonyms: | H2AX; H2A.X; H2A/X |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] |
Category: | Primary Ab |