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查看说明书Recombinant Arrestin Beta 1 (ARRb1)
Cat#:TP05467应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-beta Arrestin 1 (Ser412) Rabbit pAb |
| Cat No.: | DPA05470 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:5000 IHC: 1:100 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser412 of human beta Arrestin 1 |
| Calculated Molecular Weight: | 50 kDa |
| Observed Molecular Weight: | 50 kDa |
| GenBank Accession Number: | P49407 |
| Gene ID (NCBI): | 408 |
| Synonyms: | ARB1; ARR1 |
| Background: | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011] |
| Category: | Primary Ab |
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