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Phospho-AMPK alpha 1 (Ser496) Rabbit pAb

Cat No.: DPA05473
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Product Name: Phospho-AMPK alpha 1 (Ser496) Rabbit pAb
Cat No.: DPA05473
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,IP
Recommended Dilution: WB: 1:10001:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser496 of human AMPK alpha 1
Calculated Molecular Weight: 64 kDa
Observed Molecular Weight: 64 kDa
GenBank Accession Number: Q13131
Gene ID (NCBI): 5562
Synonyms: AMPK; AMPKa1
Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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