Recombinant Human CaM Kinase II Subunit β/CAMK2B Protein(C-6His)
Cat#:TP06098应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Phospho-CaMKII alpha/beta (Thr286) Rabbit pAb |
Cat No.: | DPA05505 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr286 of human CaMKII alpha/beta |
Calculated Molecular Weight: | 54 kDa |
Observed Molecular Weight: | 54 kDa |
GenBank Accession Number: | Q13554 |
Gene ID (NCBI): | 815 |
Synonyms: | CAMKA |
Background: | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008] |
Category: | Primary Ab |