Phospho-NFAT2 (Ser237) Rabbit pAb
Cat#:DPA05513应用:WB,FC
Product Name: | Phospho-NFAT2 (Ser237) Rabbit pAb |
Cat No.: | DPA05513 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,FC |
Recommended Dilution: | WB: 1:1000 FC: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser237 of human NFAT2 |
Calculated Molecular Weight: | 101 kDa |
Observed Molecular Weight: | 101 kDa |
GenBank Accession Number: | O95644 |
Gene ID (NCBI): | 4772 |
Synonyms: | NFAT2; NFATc; NF-ATC; NF-ATc1.2 |
Background: | The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013] |
Category: | Primary Ab |