Cytokeratin 8 Rabbit pAb
Cat#:DPA05228应用:WB,IHC,ICC/IF,FC,IP
Product Name: | Phospho-Cytokeratin 8 (Ser23) Rabbit pAb |
Cat No.: | DPA05534 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,IP |
Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser23 of human Cytokeratin 8 |
Calculated Molecular Weight: | 54 kDa |
Observed Molecular Weight: | 54 kDa |
GenBank Accession Number: | P05787 |
Gene ID (NCBI): | 3856 |
Synonyms: | K8; KO; CK8; CK-8; CYK8; K2C8; CARD2 |
Background: | This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
Category: | Primary Ab |