蛋白
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检测试剂盒
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分子生物学
规格：
查看说明书c-Myc Rabbit pAb
Cat#:DPA04659应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-c-Myc (Ser62) Rabbit pAb |
| Cat No.: | DPA05544 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser62 of human c-Myc |
| Calculated Molecular Weight: | 49 kDa |
| Observed Molecular Weight: | 57 kDa |
| GenBank Accession Number: | P01106 |
| Gene ID (NCBI): | 4609 |
| Synonyms: | MRTL; MYCC; c-Myc; bHLHe39 |
| Background: | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
| Category: | Primary Ab |
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