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Phospho-p95 NBS1 (Ser343) Rabbit pAb

Cat No.: DPA05562
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Product Name: Phospho-p95 NBS1 (Ser343) Rabbit pAb
Cat No.: DPA05562
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20-1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser343 of human p95 NBS1
Calculated Molecular Weight: 85 kDa
Observed Molecular Weight: 95 kDa
GenBank Accession Number: O60934
Gene ID (NCBI): 4683
Synonyms: ATV; NBS; P95; NBS1; AT-V1; AT-V2
Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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