BUBR1 Rabbit pAb
Cat#:DPA01057应用:WB,IHC,FC,IP
Product Name: | Phospho-BubR1 (Thr680) Rabbit pAb |
Cat No.: | DPA05563 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr680 of human BubR1 |
Calculated Molecular Weight: | 120 kDa |
Observed Molecular Weight: | 120 kDa |
GenBank Accession Number: | O60566 |
Gene ID (NCBI): | 701 |
Synonyms: | MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta |
Background: | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |