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Phospho-BubR1 (Thr680) Rabbit pAb

Cat No.: DPA05563
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Product Name: Phospho-BubR1 (Thr680) Rabbit pAb
Cat No.: DPA05563
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr680 of human BubR1
Calculated Molecular Weight: 120 kDa
Observed Molecular Weight: 120 kDa
GenBank Accession Number: O60566
Gene ID (NCBI): 701
Synonyms: MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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