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Phospho-Cdk1/Cdk2/Cdk3 (Thr14) Rabbit pAb

Cat No.: DPA05602
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Product Name: Phospho-Cdk1/Cdk2/Cdk3 (Thr14) Rabbit pAb
Cat No.: DPA05602
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,IP
Recommended Dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr14 of human Cdk1
Calculated Molecular Weight: 34 kDa
Observed Molecular Weight: 34 kDa
GenBank Accession Number: P06493
Gene ID (NCBI): 983
Synonyms: CDC2; CDC28A; P34CDC2
Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Category: Primary Ab
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