蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书MDM2 Rabbit pAb
Cat#:DPA01433应用：WB,ICC/IF,IP
| Product Name: | Phospho-MDM2 (Ser166) Rabbit pAb |
| Cat No.: | DPA05613 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:5000-1:20000 IHC: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser166 of human MDM2 |
| Calculated Molecular Weight: | 55 kDa |
| Observed Molecular Weight: | 90 kDa |
| GenBank Accession Number: | Q00987 |
| Gene ID (NCBI): | 4193 |
| Synonyms: | HDMX; hdm2; ACTFS |
| Background: | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] |
| Category: | Primary Ab |
相关产品
