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规格：
查看说明书Cdc6 Rabbit pAb
Cat#:DPA04371应用：WB,IHC,ICC/IF
| Product Name: | Phospho-Cdc6 (Ser54) Rabbit pAb |
| Cat No.: | DPA05620 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser54 of human Cdc6 |
| Calculated Molecular Weight: | 63 kDa |
| Observed Molecular Weight: | 63 kDa |
| GenBank Accession Number: | Q99741 |
| Gene ID (NCBI): | 990 |
| Synonyms: | CDC18L; HsCDC6; MGORS5; HsCDC18 |
| Background: | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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