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查看说明书ZAP70 Rabbit pAb
Cat#:DPA04655应用：WB,FC,IP
| Product Name: | Phospho-ZAP70 (Tyr292) Rabbit pAb |
| Cat No.: | DPA05627 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr292 of human ZAP70 |
| Calculated Molecular Weight: | 70 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | P43403 |
| Gene ID (NCBI): | 7535 |
| Synonyms: | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
| Background: | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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