Recombinant Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1)
Cat#:TP01993应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Phospho-EIF2S1 (Ser51) Rabbit pAb |
Cat No.: | DPA05634 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser51 of human EIF2S1 |
Calculated Molecular Weight: | 36 kDa |
Observed Molecular Weight: | 36 kDa |
GenBank Accession Number: | P05198 |
Gene ID (NCBI): | 1965 |
Synonyms: | EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha |
Background: | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010] |
Category: | Primary Ab |