蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Caveolin-1 Rabbit pAb
Cat#:DPA01145应用：WB,IHC,ICC/IF
| Product Name: | Phospho-Caveolin-1 (Tyr14) Rabbit pAb |
| Cat No.: | DPA05640 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr14 of human Caveolin-1 |
| Calculated Molecular Weight: | 21 kDa |
| Observed Molecular Weight: | 21 kDa |
| GenBank Accession Number: | Q03135 |
| Gene ID (NCBI): | 857 |
| Synonyms: | CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085 |
| Background: | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] |
| Category: | Primary Ab |
相关产品
