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查看说明书PLCG 2 Rabbit pAb
Cat#:DPA04161应用：WB,IHC,FC,IP
| Product Name: | Phospho-PLCG 2 (Tyr1197) Rabbit pAb |
| Cat No.: | DPA05670 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:2000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr1197 of human PLCG 2 |
| Calculated Molecular Weight: | 148 kDa |
| Observed Molecular Weight: | 148 kDa |
| GenBank Accession Number: | P16885 |
| Gene ID (NCBI): | 5336 |
| Synonyms: | FCAS3; APLAID; PLC-IV; PLC-gamma-2 |
| Background: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014] |
| Category: | Primary Ab |
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