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Phospho-SLP76 (Tyr145) Rabbit pAb

Cat No.: DPA05677
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Product Name: Phospho-SLP76 (Tyr145) Rabbit pAb
Cat No.: DPA05677
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr145 of human SLP76
Calculated Molecular Weight: 60 kDa
Observed Molecular Weight: 76 kDa
GenBank Accession Number: Q13094
Gene ID (NCBI): 3937
Synonyms: SLP76; SLP-76
Background: This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
Category: Primary Ab
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