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查看说明书Phospho-MSK1 (Ser376) Rabbit pAb
Cat#:DPA05340应用：WB,IHC,ICC/IF,IP
| Product Name: | Phospho-MSK1 (Ser360) Recombinant Rabbit mAb |
| Cat No.: | RMA02943 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:2000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser360 of human MSK1 |
| Calculated Molecular Weight: | 90 kDa |
| Observed Molecular Weight: | 90 kDa |
| GenBank Accession Number: | O75582 |
| Gene ID (NCBI): | 9252 |
| Synonyms: | MSK1; RLPK; MSPK1 |
| Background: | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. |
| Category: | Primary Ab |
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