Acetyl Coenzyme A Carboxylase Rabbit pAb
Cat#:DPA02528应用:WB,IHC,ICC/IF,FC
Product Name: | Phospho-Acetyl Coenzyme A Carboxylase (Ser79) Recombinant Rabbit mAb |
Cat No.: | RMA02982 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000-1:5000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser79 of human Acetyl Coenzyme A Ca |
Calculated Molecular Weight: | 277 kDa |
Observed Molecular Weight: | 277 kDa |
GenBank Accession Number: | O00763 |
Gene ID (NCBI): | 31 |
Synonyms: | ACC; ACAC; ACC1; ACCA; ACACAD |
Background: | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |