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查看说明书Recombinant Human ACLY / acly / ATP citrate lyase Protein (His tag)
Cat#:TP07052应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-ATP citrate lyase (Thr447/Ser451) Recombinant Rabbit mAb |
| Cat No.: | RMA02993 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ATP citrate |
| Calculated Molecular Weight: | 121 kDa |
| Observed Molecular Weight: | 121 kDa |
| GenBank Accession Number: | P53396 |
| Gene ID (NCBI): | 47 |
| Synonyms: | ACL; ATPCL; CLATP |
| Background: | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014] |
| Category: | Primary Ab |
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