蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书MEK4 Rabbit pAb
Cat#:DPA03075应用：WB
| Product Name: | Phospho-MEK4 (Ser80) Recombinant Rabbit mAb |
| Cat No.: | RMA03039 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4 |
| Calculated Molecular Weight: | 44 kDa |
| Observed Molecular Weight: | 44 kDa |
| GenBank Accession Number: | P45985 |
| Gene ID (NCBI): | 6416 |
| Synonyms: | JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1 |
| Background: | This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Category: | Primary Ab |
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