FAK Rabbit pAb
Cat#:DPA01175应用:WB,IHC,ICC/IF,FC,IP
Product Name: | Phospho-FAK (Tyr397) Recombinant Rabbit mAb |
Cat No.: | RMA03078 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ICC/IF |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr397 of human FAK |
Calculated Molecular Weight: | 119 kDa |
Observed Molecular Weight: | 119 kDa |
GenBank Accession Number: | Q05397 |
Gene ID (NCBI): | 5747 |
Synonyms: | FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK |
Background: | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017] |
Category: | Primary Ab |