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查看说明书Recombinant Human ATF2 Protein (His & GST tag)
Cat#:TP07053应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-ATF2 (Thr71) Recombinant Rabbit mAb |
| Cat No.: | RMA03082 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB, ICC/IF, IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:100 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2 |
| Calculated Molecular Weight: | 55 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | P15336 |
| Gene ID (NCBI): | 1386 |
| Synonyms: | HB16; CREB2; TREB7; CREB-2; CRE-BP1 |
| Background: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] |
| Category: | Primary Ab |
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