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分子生物学
规格：
查看说明书PKC alpha Rabbit pAb
Cat#:DPA04393应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-PKC alpha (Thr638) Recombinant Rabbit mAb |
| Cat No.: | RMA03088 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC, ICC/IF, IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr638 of human PKC alpha |
| Calculated Molecular Weight: | 77 kDa |
| Observed Molecular Weight: | 80 kDa |
| GenBank Accession Number: | P17252 |
| Gene ID (NCBI): | 5578 |
| Synonyms: | AAG6; PKCA; PRKACA; PKC-alpha |
| Background: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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