Recombinant Human Tumor necrosis factor receptor superfamily member 6 Protein
Cat#:TP04346应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein (Fc tag) |
Cat No.: | TP08268 |
TargetID: | P25445 |
Source: | HEK293 Cells |
Gene Accession Number: | 355 |
Peptide Sequence: | Met 1-Glu 173 |
Tag: | C-Fc |
Purity: | >95% as determined by SDS-PAGE. |
Formulation: | Freeze-dried powder |
Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
Category: | Protein |
Species Reactivity: | Human |
Predicted Molecular Mass: | 43.4 kDa |
Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
Background: | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis |
Size: | 10ug 50ug 100ug 200ug 1mg |
Synonyms: | ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6 |