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Recombinant Human IL1R2 / IL1RB / CD121b Protein (His tag)

Cat No.: TP08441
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  • 15% SDS-PAGE Reduced

Product Name: Recombinant Human IL1R2 / IL1RB / CD121b Protein (His tag)
Cat No.: TP08441
TargetID: P27930
Source: HEK293 Cells
Gene Accession Number: 7850
Peptide Sequence: Met 1-Glu 343
Tag: C-His
Purity: >85% as determined by SDS-PAGE.
Formulation: Freeze-dried powder
Storage Buffer: Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose
Storage Condition: Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen
Category: Protein
Species Reactivity: Human
Predicted Molecular Mass: 39.3 kDa
Applications: Positive Control; Immunogen; SDS-PAGE; WB
Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Size: 10ug  50ug  100ug  200ug  1mg
Synonyms: CD121b;CDw121b;IL-1R-2;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB
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