Recombinant Human BMPR1A Protein
Cat#:TP01354应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Recombinant Human BMPRIA / ALK-3 / CD292 Protein (His & Fc tag) |
| Cat No.: | TP08519 |
| TargetID: | P36894 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 657 |
| Peptide Sequence: | Met 1-Arg 152 |
| Tag: | C-His & Fc |
| Purity: | >85% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 42 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | 10q23del;ACVRLK3;ALK3;CD292;SKR5 |