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TLR2 Rabbit pAb

Cat No.: DPA01015
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Product Name: TLR2 Rabbit pAb
Cat No.: DPA01015
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human TLR2
Calculated Molecular Weight: 90 kDa
Observed Molecular Weight: 90 kDa
GenBank Accession Number: O60603
Gene ID (NCBI): 7097
Synonyms: TIL4; CD282
Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Category: Primary Ab
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