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查看说明书Recombinant Mouse EphA2 Protein (His tag)
Cat#:TP05597应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Ephrin receptor A2 Rabbit pAb |
| Cat No.: | DPA01018 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse, Rat |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse Ephrin receptor A2 |
| Calculated Molecular Weight: | 109 kDa |
| Observed Molecular Weight: | 125 kDa |
| GenBank Accession Number: | Q03145 |
| Gene ID (NCBI): | 13836 |
| Synonyms: | Eck; Myk2; Sek2; Sek-2; AW545284 |
| Background: | Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 signaling pathway. |
| Category: | Primary Ab |
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