蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Daxx Rabbit pAb
Cat#:DPA01053应用：WB,IHC,ICC/IF,FC
| Product Name: | Daxx Rabbit pAb |
| Cat No.: | DPA01053 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:2000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Daxx |
| Calculated Molecular Weight: | 81 kDa |
| Observed Molecular Weight: | 110 kDa |
| GenBank Accession Number: | Q9UER7 |
| Gene ID (NCBI): | 1616 |
| Synonyms: | DAP6; EAP1; BING2; SMIM40 |
| Background: | This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008] |
| Category: | Primary Ab |
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