蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书ACTL6A Rabbit pAb
Cat#:DPA01064应用：WB,IHC,ICC/IF,IP
| Product Name: | ACTL6A Rabbit pAb |
| Cat No.: | DPA01064 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human ACTL6A |
| Calculated Molecular Weight: | 48 kDa |
| Observed Molecular Weight: | 48 kDa |
| GenBank Accession Number: | O96019 |
| Gene ID (NCBI): | 86 |
| Synonyms: | Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA |
| Background: | This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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