蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Zyxin Rabbit pAb
Cat#:DPA01109应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Zyxin Rabbit pAb |
| Cat No.: | DPA01109 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:20-1:100 FC: 1:200-1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Zyxin |
| Calculated Molecular Weight: | 61 kDa |
| Observed Molecular Weight: | 78 kDa |
| GenBank Accession Number: | Q15942 |
| Gene ID (NCBI): | 7791 |
| Synonyms: | ESP-2; HED-2 |
| Background: | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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