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SET Rabbit pAb

Cat No.: DPA01127
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Product Name: SET Rabbit pAb
Cat No.: DPA01127
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:2000-1:10000
IHC: 1:50
ICC/IF: 1:200
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human SET
Calculated Molecular Weight: 34 kDa
Observed Molecular Weight: 39 kDa
GenBank Accession Number: Q01105
Gene ID (NCBI): 6418
Synonyms: 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA
Background: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Category: Primary Ab
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