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Staufen Rabbit pAb

Cat No.: DPA01148
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Product Name: Staufen Rabbit pAb
Cat No.: DPA01148
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:50
ICC/IF: 1:100
FC: 1:200-1:500
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Staufen
Calculated Molecular Weight: 63 kDa
Observed Molecular Weight: 63 kDa
GenBank Accession Number: O95793
Gene ID (NCBI): 6780
Synonyms: STAU; PPP1R150
Background: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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