蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Cortactin Rabbit pAb
Cat#:DPA01231应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Cortactin Rabbit pAb |
| Cat No.: | DPA01231 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:5000-1:10000 IHC: 1:20-1:100 ICC/IF: 1:200 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Cortactin |
| Calculated Molecular Weight: | 62 kDa |
| Observed Molecular Weight: | 80-85 kDa |
| GenBank Accession Number: | Q14247 |
| Gene ID (NCBI): | 2017 |
| Synonyms: | EMS1 |
| Background: | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
| Category: | Primary Ab |
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