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分子生物学
规格：
查看说明书Recombinant Mouse PKC delta / PRKCD Protein (His & GST tag)
Cat#:TP06436应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | PKC delta Rabbit pAb |
| Cat No.: | DPA01237 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20-1:500 ICC/IF: 1:100 FC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human PKC delta |
| Calculated Molecular Weight: | 78 kDa |
| Observed Molecular Weight: | 78 kDa |
| GenBank Accession Number: | P28867 |
| Gene ID (NCBI): | 18753 |
| Synonyms: | Pkcd; PKC[d]; AI385711; PKCdelta; D14Ertd420e |
| Background: | Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self-antigen induced B cell tolerance induction. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. |
| Category: | Primary Ab |
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