Recombinant Human NEDD8 Protein
Cat#:TP03138应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | NEDD8 Rabbit pAb |
Cat No.: | DPA01239 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human NEDD8 |
Calculated Molecular Weight: | 9 kDa |
Observed Molecular Weight: | 9 kDa |
GenBank Accession Number: | Q15843 |
Gene ID (NCBI): | 4738 |
Synonyms: | NEDD-8 |
Background: | Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. |
Category: | Primary Ab |