COX1/Cyclooxygenase 1 Rabbit pAb
Cat#:DPA01268应用:WB,IHC,ICC/IF,FC,IP
Product Name: | COX1/Cyclooxygenase 1 Rabbit pAb |
Cat No.: | DPA01268 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:20-1:100 FC: 1:20 IP: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human COX1/Cyclooxygenase 1 |
Calculated Molecular Weight: | 69 kDa |
Observed Molecular Weight: | 69 kDa |
GenBank Accession Number: | P23219 |
Gene ID (NCBI): | 5742 |
Synonyms: | COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1 |
Background: | This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Category: | Primary Ab |