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STAT2 Rabbit pAb

Cat No.: DPA01302
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Product Name: STAT2 Rabbit pAb
Cat No.: DPA01302
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human STAT2
Calculated Molecular Weight: 98 kDa
Observed Molecular Weight: 98 kDa
GenBank Accession Number: P52630
Gene ID (NCBI): 6773
Synonyms: P113; IMD44; ISGF-3; STAT113
Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Category: Primary Ab
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