Recombinant Human PGK1 Protein
Cat#:TP03378应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | PGK1 Rabbit pAb |
Cat No.: | DPA01303 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human PGK1 |
Calculated Molecular Weight: | 45 kDa |
Observed Molecular Weight: | 45 kDa |
GenBank Accession Number: | P00558 |
Gene ID (NCBI): | 5230 |
Synonyms: | PGKA; MIG10; HEL-S-68p |
Background: | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014] |
Category: | Primary Ab |