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PGK1 Rabbit pAb

Cat No.: DPA01303
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Product Name: PGK1 Rabbit pAb
Cat No.: DPA01303
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human PGK1
Calculated Molecular Weight: 45 kDa
Observed Molecular Weight: 45 kDa
GenBank Accession Number: P00558
Gene ID (NCBI): 5230
Synonyms: PGKA; MIG10; HEL-S-68p
Background: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
Category: Primary Ab
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