蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human CD146 / MCAM Protein (His tag)
Cat#:TP07208应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CD146 Rabbit pAb |
| Cat No.: | DPA01308 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human CD146 |
| Calculated Molecular Weight: | 72 kDa |
| Observed Molecular Weight: | 120 kDa |
| GenBank Accession Number: | P43121 |
| Gene ID (NCBI): | 4162 |
| Synonyms: | CD146; MUC18 |
| Background: | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
| Category: | Primary Ab |
相关产品
