蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Bak Rabbit pAb
Cat#:DPA01330应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Bak Rabbit pAb |
| Cat No.: | DPA01330 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Bak |
| Calculated Molecular Weight: | 23 kDa |
| Observed Molecular Weight: | 23 kDa |
| GenBank Accession Number: | Q16611 |
| Gene ID (NCBI): | 578 |
| Synonyms: | BAK; CDN1; BCL2L7; BAK-LIKE |
| Background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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