蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书LRP1 Rabbit pAb
Cat#:DPA01353应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | LRP1 Rabbit pAb |
| Cat No.: | DPA01353 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:20-1:500 ICC/IF: 1:100 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human LRP1 |
| Calculated Molecular Weight: | 85 kDa |
| Observed Molecular Weight: | 85 kDa |
| GenBank Accession Number: | Q07954 |
| Gene ID (NCBI): | 4035 |
| Synonyms: | APR; KPA; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R |
| Background: | This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015] |
| Category: | Primary Ab |
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