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Cdk6 Rabbit pAb

Cat No.: DPA01363
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Product Name: Cdk6 Rabbit pAb
Cat No.: DPA01363
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:5000-1:10000
IHC: 1:20-1:100
ICC/IF: 1:50
FC: 1:20-1:100
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Cdk6
Calculated Molecular Weight: 37 kDa
Observed Molecular Weight: 37 kDa
GenBank Accession Number: Q00534
Gene ID (NCBI): 1021
Synonyms: MCPH12; PLSTIRE
Background: The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]
Category: Primary Ab
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