蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Girdin Rabbit pAb
Cat#:DPA01368应用：WB,ICC/IF,FC,IP
| Product Name: | Girdin Rabbit pAb |
| Cat No.: | DPA01368 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:200 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Girdin |
| Calculated Molecular Weight: | 216 kDa |
| Observed Molecular Weight: | 216 kDa |
| GenBank Accession Number: | Q3V6T2 |
| Gene ID (NCBI): | 55704 |
| Synonyms: | APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212 |
| Background: | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| Category: | Primary Ab |
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